In English

Development of a semi-automated covalent binding methodology

Jesper Nilsson
Göteborg : Chalmers tekniska högskola, 2010.
[Examensarbete på avancerad nivå]

A semi-automated in vitro covalent binding assay with the marketed compounds acetaminophen, amodiaquine, carbamazepine, clozapine, diclofenac, troglitazone, and zomepirac has been used to evaluate the applicability of a zone classification system proposed by Nakayama, et al., 2009*. The zone classification system takes into consideration daily dose of each drug together with the generated amount of covalent binding from the assay. *Reference in thesis



Publikationen registrerades 2010-11-11. Den ändrades senast 2013-04-04

CPL ID: 128850

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